Advancing Career Development. Personal and Professional Profile Essay

Advancing Career Development. Personal and Professional Profile - Essay Example Categorical initiatives could benefit the industry, but there is a broader push on the component of the regime to try out and promote salubrious healthy living. Factors like utility prices and salary rates will have an impact on numerous aspects of the industry, as costs will elevate and customers may need to prioritize their expenditure as their disposable income are cut down. From the PESTEL analysis of the three companies, namely Fitness First, Virgin Active, and Gold’s Gym companies, it is evident that people have placed their health first before everything else. Most of their management skills have been enhanced to keep the clients satisfied and eager to search for better health opportunities. It is also true that in most fitness centers, customers who are satisfied with the services come back often and build a good reputation for the companies. General Managers are normally responsible for daily operations of a business. Planning, Monitoring and Controlling is what they need to do. Responsibilities also include hiring or training staff members and to deal with clients. Business Development Managers are needed in the Health and Beauty Industry as the market becomes more and more occupied and as competition level increases. That is why it is vital to have a specialist, who is focused on innovations and improvements. When analysing business processes, I was able to identify important issues and made some useful recommendations, like the development of a web-site and advertising of new products and services via texts to the customer base I am an experienced strategic planner and consultant with proven results in a variety of industries. My entrepreneurial spirit has permitted me to achieve established success, along with my understanding of market trends and implementing processes to grow and expand products and services. I have proven organizational and time-management skills, with extensive knowledge of Design Process

Empirical paper on international finance or open economy Essay

Empirical paper on international finance or open economy macroeconomics - Essay Example A deep and well-supervised financial sector is essential for efficiently intermediating foreign finance into productive investments. It has also been shown to reduce the adverse effects of capital flow volatility. Countries with better institutions attract relatively more foreign direct investments and portfolio equity flows, which are more stable than debt flows, and as a result, the likelihood of promoting indirect benefits. For each of the threshold category, an appropriate and conceptually sound measure was chosen. Financial depth; the proxy used for financial depth is the ratio of private credit to GDP. Also include in the measure of financial depth and development are stock market capitalization sum and credit to the national GDP, the ratio of GDP and institution measures such as creditors’ rights ii. Institution quality; the proxy used to get aggregate institutional quality get derived from a simple average of the six World Bank Governance Indicators (WBGI). The six aspects of institutional quality covered by WBGI are: violence and profit stability; accountability and voice; quality of the regulatory; government effectiveness; the rule of law and control of corruption. iii. Regulation; the proxy used is an index of the rigidity of labor regulations from the International Finance Corporation’s Doing Business Database. The database captures an economy’s ability to adapt to changing business conditions that include financial flows. Since data is only available from 2003, average for each country is used as a fixed regulation variable. iv. Trade openness; the totals of imports and exports of goods and services, expressed as a ratio to GDP is used as the proxy. The measure of policy openness to trade can be defined as the proportion or level of years for which the trade regime/ era is an open one also got included. v. Macro policies; the

Huge Inflammatory Myofibroblastic Tumor in Teenager

Huge Inflammatory Myofibroblastic Tumor in Teenager Abstract Background: Inflammatory myofibroblastic tumor (IMT) is a rare benign neoplasm. The huge IMT of chest is even rarely observed and there is few literatures described the disease. Case presentation: A 17-year-old girl who suffered from a dry cough with right chest pain. Contrast-enhanced CT showed a huge heterogeneous mass with calcified plaques. A surgical management strategy was successfully undertaken. Increasing physician awareness of this entity should facilitate recognition of its clinical characteristics and laboratory findings. Conclusions: This case suggests that a rarely huge and surgically treated IMT in a teenager and concerned with the radioclinical, histopathological, therapeutic aspects of this disease. Keywords Inflammatory myofibroblastic tumor, Lung, Surgery Background Inflammatory myofibroblastic tumor (IMT) is a rare benign tumor that often affects children. It has been first described by Brunn in 1939 [1] and it accounts for 0.71% of all lung tumors. [2, 3]. The origin of the IMT is unknown, but recent studies have shown that it is a true tumor rather than a reaction process [4]. Different terms used to describe IMT include inflammatory pseudotumor, cellular inflammatory pseudotumor, plasma cell granuloma and inflammatory fibrosarcoma. This lesion consists of inflammatory cells and myofibroblastic spindle cells [5, 6]. We report a case with a rarely huge and surgically treated IMT in a teenager and concerned with the radioclinical, histopathological, therapeutic aspects of this disease. Case presentation A 17-year-old girl was referred to our hospital with a 15 days history of right chest and cough without sputum. She denied the following symptoms including the presence ofhoarseness, hemoptysis, anddyspnea. Her medical history and family history were uneventful. Physical examination revealed normal breath sounds in both of the lung fields. The results of laboratory examinations, including arterial blood gases, hematology tests and biochemistry tests, were within normal limits. Her Pulmonary function tests and cardiovascular examination revealed normal performance. Contrast-enhanced chest computed tomography (CT) showed an 18Ãâ€"16Ãâ€"15 cm heterogeneous mass with calcified plaques invading the entire right hemithorax and mediastinal shift to the left (Fig 1A, 1B). However, the patient refused to have the bronchoscopic examination and fine-needle biopsy of the mass. As diagnosis was not established through imaging, surgery was scheduled. Under general anesthesia with selective intub ation, a huge mass (measuring 20Ãâ€"17Ãâ€"17 cm and weighing 2010g) with inferior vena cava and right pericardium invasion was found and the right middle and lower lobes bronchus appeared encased by the mass. At last, the neoplasm was completely excised. The patient underwent a right middle and lower lobectomy, inferior vena cava angioplasty and partial resection of pericardium. Mediastinal lymph node dissection was also accomplished. The feeding vessels of the mass were ligated and the mass was removed without tumor spillage or capsular injury. After that, reexpansion of the right upper lobe was observed and a chest tube was placed to drain the pleural cavity. A postoperative roentgenogram of the chest showed that the mediastinum had returned to its normal position and the right lung was well expanded. Microscopic examination revealed a proliferation of regular spindle cells arrayed in fascicles, admixed with lymphocytes, plasma cells and eosinophils. Additional immunohistochemis try with anaplastic lymphoma kinase (ALK)-1 and smooth muscle actin (SMA) revealed positive and the translocation of the ALK gene was found by fluorescence in situ hybridisation (FISH). The results for desmin, S-100, CD99, CD34, Myogenin, EMA and pankeratin were negative. Ki-67 proliferative activity was 8%. Based on these data, the diagnosis of inflammatory myofibroblastic tumor was retained. Histologic diagnosis showed a negative bronchial margin and lymph nodes free of malignancy. The patient made an uneventful postoperative recovery and was followed up for two months without evidence of recurrence to date. Conclusions Inflammatory myofibroblastic tumor (IMT) is a rare massforming lesion characterized by fibroblastic or myofibroblastic spindle cell proliferation with varying degrees of inflammatory cell infiltration. The World Health Organization (WHO) classified IMT as a distinct entity in 1994 [7]. However, the huge inflammatory myofibroblastic tumor of chest is even rarely observed and there is few literatures described the disease (Table). The cause of IMT tumors is unclear, but an immunological response to an infectious agent or noninfectious agent remains possible [8]. Whereas some reporters demonstrated that IMT tumors are true neoplasms and some believe the IMT tumors to be a low-grade sarcoma with inflammatory cells as it has a potential for local recurrence, infiltration, multicentricity, and rarely metastases [9]. Also, ALK positivity is detected in 36% to 60% of cases and the presence of chromosomal aberrations in these tumors suggests that IMT is a neoplastic proliferation of clonal or igin [10]. In our case, there was no evidence of infection or inflammatory response and no history of trauma in her chest. The tumor was single and circumscribed, and movable. The IMT affects both sexes, at any ages, with a slight predominance in children and young adults [4, 11]. Most patients are asymptomatic and the tumor is discovered incidentally on a chest X-ray performed for another reason [4, 11].From the table, all of the four patients were young adults and were referred to the hospital with a common symptom of cough. In our patient, the tumor was discovered at an early age and the only symptoms were dry cough and right chest pain. Radiological aspects are capricious. Chest radiographs are the most generally performed imaging study to evaluate the neoplasm. Most patients have a mass or a pulmonary nodule, generally measuring 1 to 6 cm in diameter [12]. On CT scans, these tumors shows typically heterogenous attenuating enhancement [6]. Sometimes the tumor can extend towards the hilum, mediastinum, pleura or diaphragm [1, 3]. As recorded in the table, all the sizes of masses were huge and two of them were observed the invasion of the mediastinal or the chest wall. There is also a word of caution in our case that the representative calcifications were observed in the centure of heterogeneous mass and it invaded the inferior vena cava and right pericardium. Microscopically the IMT tumor consists of spindle shaped cells that are mixed with a chronic inflammatory component that consists of plasma cells, lymphocytes, and occasional histiocytes. Immunohistochemistry for ALK discovered cytogenetic abnormalities on chromosome 2p23 is relatively specific for IMF tumor among the spectrum of fibroblastic-myofibroblastic tumors and other potential mesenchymal mimics of IMF tumor [13]. The recent WHO classification of soft tissue tumors recognizes 3 basic variants of IMT: (1) loosely organized myofibroblasts in an edematous myxoid background with plasma cells, lymphocytes, eosinophils, and blood vessels, resembling nodular fasciitis; (2) dense aggregates of spindle cells arrayed in a variable myxoid and collagenized background and admixed with a distinctive inflammatory infiltrate, diffuse clusters of plasma cells, and lymphoid nodules, resembling fibrous histiocytoma or fibromatosis; and (3) collagen sheets with scattered plasma cells and eosinop hils resembling a scar or desmoid tumor [14]. The differential diagnosis of IMT is follicular dendritic cell tumor and inflammatory pseudotumor. Follicular dendritic cell sarcoma (FDCS), which was first reported by Monda et al. in 1986, is a rare neoplastic proliferation that exhibits the morphological and immunophenotypic features of FDCS that are among the accessory cells of the lymphoid system. The tumor cells exhibited positive immunohistochemical staining for vimentin, CD21 and CD35 as well as negative staining for ALK-1 and SMA. Inflammatory pseudotumors are benign tumors commonly found in the lung and they are characterized by proliferation of spindle cells (fibroblasts and myoblasts), with variable numbers of mitoses, and inflammatory cells infiltration, particularly plasma cells. More recently, the presence of anaplastic lymphoma kinase (ALK 1) staining in some cases has been postulated to be of value in the confirmation of IMT and in its distinction from other entities. A series of studies found the translocation of th e ALK gene by fluorescence in situ hybridisation (FISH) in IMT (16). In our case, the mass was spindle cell lesion with severe atypism and some mitosis. As shown in Fig 2 (A, B, C), ganglion-like cells were present and the immunohistochemistry result for ALK-1 shows strong positivity of tumor cytoplasm and translocation of the ALK gene. Based on these findings, her tumor may be very aggressive. Despite IMT is a benign tumor, it is considered by some authors as a low grade tumor because of malignant features such as local invasiveness, recurrence or malignant transformation. Complete surgical resection is the appropriate treatment for IMT. Cerfolio and colleagues reported an excellent prognosis in patients undergoing complete resection of pulmonary IMT, with a 5-year survival rate of 91.3%. However, a 60% recurrence rate in those receiving incomplete resection has been reported in the same study [15]. Corticosteroid monotherapy may result in rapid resolution of the disease and sustained remission (17, 18). Non-steroidal anti-inflammatory agents (NSAIDs) as solitary therapy may be extremely efficacious and anecdotal response to chemotherapy has also been reported (19). As the literature reviewed in the table, three patients had the operations by a standard posterolateral thoracotomy. Among them, two patients had the lobectomy and the other had the complete resection with two through fourth ribs. The patient whose neoplasm invaded superior vena cava, heart atrium and right pulmonary vein underwent chemotherapy with bleomicin, etoposide and cisplatin. After two cycles of chemotherapy, the tumorslightly reduced in size and the patient only survived for 12 months. In summary, inflammatory myofibroblastic tumor is a rare benign tumor. Because of its local invasiveness and its tendency to recur, IMT tumor can be confused with malignant lesions. Because the treatment of IMT tumor is conservative surgery, preoperative recognition is important to avoid radiation therapy, and intensive multi-agent chemotherapy that would be appropriate treatments for soft tissue sarcomas. Clinical and radiological presentation is variable and nonspecific and the diagnosis is rarely made before chirurgical management. Also, because the tumor with cellular atypia, ganglion-like cells, ALK and SMA reactivity has a more aggressive clinical behavior, a careful follow-up is required. Figure legend Figure 1: CT features of the case. A and B: Contrast-enhanced CT showed a huge heterogeneous mass with calcified plaques. Figure 2: Histological and immunoistochemical features. A: Hematoxylin-eosin staining demonstrating spindle cells sprinkled, with a predominance of plasma cells and lymphocytes. (X400) B: Immunohistochemical staining showing strong reactivity for anaplastic lymphoma kinase (ALK)-1(X400) C: Immunohistochemical staining showing strong reactivity for smooth muscle actin (SMA) (X400) 1

Hamlet: Power vs Happiness :: Shakespeare Hamlet Essays

Claudius what are your motives for killing the king, marrying his wife and taking on the role of father to his young son?      Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   Claudius is introduced in act I, ii.   In this scene he has an important speech. In this speech he talks about the death of the king, his marriage to the queen and the foreign problems of the state. He utilizes many transitions and tends to empiseze the foreign affairs of the state. I don't know what to make of this, it could mean various things. It could mean that Claudius is making a grab for power shown in his concentration on the foreign polices trying to distract from his lust for power, along with his marriage to the queen giving the change in leadership a smoother and more acceptable feel. He also down plays the death of the formal king so that he can redirect the peoples' attention to his plans and the problems of the state. But I could mean something else I'm not sure. Later on in this scene Claudius talks to Hamlet, Hamlet is very depressed, Claudius gives hamlet some comforting and fatherly advice here trying to get him out of his deep depression. But what is his true motivation here is he trying to get hamlet as a backer for his new rain, so he is just   lying and manipulating hamlet, or dose he have true and deep feelings for Hamlet and is just trying to help hamlet and was no self-interest in it. I feel right now that   it a bit of both I think   he cares about hamlet but would also like him to support his rise to power.      Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   Next we come to act II, ii,   hamlet has made many strange comments and actions lately, many people think he is going, or has gone insane. Claudius finds two of Hamlets good friends to spy on him and try to find out what wrong with him. At this point we know that Hamlet knows that Claudius killed his father but we don't know whether Claudius knows that hamlet knows or even if he suspects, this cast a strange light on this scene. First if Claudius suspects hamlet knows that he killed his father then we might assume that Claudius is sending these spy to find out for sure if he knows, but if he dose not suspect hamlet then this might be another show of Claudius's affection towards Hamlet. So the same question keeps coming up dose Claudius like Hamlet or is he just using him? At this point it to hard to tell so we must delve deeper in to the

Analyzing a Published Work

Analyzing a Published Work Overview One of the most important moves academic writers can master is the art of analysis. This assignment will help you to develop the skills necessary to determine the meaning found within a text. To be clear, the intent of this essay is not to argue for or against the content; instead, we are analyzing what the article does in terms of the following: 1. purpose, 2. approach, and 3. effectiveness. Assignment Go to an online newspaper website: Chicago Tribune http://www. chicagotribune. com/, http://www. ansascity. com/, or http://www. nytimes. com/ are a few possible sites, but feel free to use a more local newspaper website. Find an article in the Op/ED section that is argumentative in nature. Use the following questions to guide your analysis: 1. What is the purpose of the text? In other words, what exactly is the position the article takes and/or what does the author want his or her readers to believe and/or do after reading the article? 2. What stra tegies does the text use to attempt to achieve its purpose? Give examples from the article.In other words, does the article use facts, examples, experiences, logic, assumptions, data, sources, expert opinion, and so on to prove his or her position? Be sure to give examples. You could also try to determine if the position is presented as more of a Classical argument or a Rogerian argument. 3. What are the strengths and weaknesses of the approach the article used? In other words, what would you have liked to see more of in the article? Less of? What worked? What didn't work? Do you detect bias that is unreasonable? Does the author use unreasonable assertions, stereotypes, or faulty information to make his or her points?Does the author place the opposition in an unfair light? Does the author distort the arguments of those who disagree? Does the author fail to recognize the weaknesses in his or her own position? Does the author leave out important information? Does the author back up hi s or her assertions with evidence, or does he or she simply make assumptions? What would most improve the argument? Explain your answers. Remember, we are not arguing for or against the content of these articles; we are analyzing what the article attempts to do, how it does it, and if it does so fairly.We should not be concerned about how we feel about the article. To be clear: Your readers should not know what your position is about the subject. Your readers should only know whether or not you felt the article was reasonable, well-developed, fair, etc. Do not include personal opinion or personal judgments about the subject matter. Do not include personal narrative. This analysis should be presented in the form of a single essay, complete with a title page, an introduction, three body paragraphs (purpose, approach, and effectiveness), a conclusion, and a full References page.Your analysis should meet the following criteria: †¢Is based on a current topic and/or event; †¢is between 300-500 words in length, not including the title page, abstract (if used), and References page; †¢includes direct quotations and paraphrased passages from the text; †¢uses attributive tags that not only work to convey the mood of the writer, but establish him or her as an authority in the field of study; †¢avoids personal opinion; †¢is written clearly, concisely, and accurately; †¢is written solely in third-person; is formatted in APA style and includes a References page; †¢has been closely edited so that it contains few or no mechanical errors; †¢is ordered with a title page, an introduction, three body paragraphs (purpose, approach, and effectiveness), a conclusion, and a full References page. *Note that no one writes a polished essay in a single sitting. Start early and give yourself time for multiple revisions. Analysis Checklist As you work on your analysis, it is a good idea to keep the following questions in mind: 1. How does this an alysis meet the assignment criteria? . How close do you feel your analysis reflected the presentation of the original argument? 3. Does this analysis use effective transitions as it progresses from paragraph to paragraph? 4. Does this analysis avoid personal opinion, casual language, or first or second person language? 5. Is there anything in this analysis that could have been left out without losing its effect? 6. Is there anything else that could have been added to this analysis to make it feel more complete? 7. Is this analysis based on a current topic?

Assassination of Archduke Franz Ferdinand

On June 28th, 1914 in the city of Sarajevo two bullets were fired. World War One, World War Two and the Cold War all trace their origins to the gunshots that interrupted that summer day. Archduke Franz Ferdinand was assassinated. Not only was Franz murdered, but so was his wife Sophie, Duchess of Hohenberg. They were assassinated by a young man named Bosnian Serb which set off a chain of events that leaded to the start of World War One. To many people it was known as the Great War and seemed to have come out of the blue. Franz’s assassination was the start to it all.Franz Ferdinand was the eldest son of Carl Ludwig and the brother of Emperor Franz Josef. Franz was born in Austria in1863. He was educated by private tutors and decided to join the Austro-Hungarian Army in 1883. His military career included service with an infantry regiment in Prague and Hungary. While in the army Franz received several promotions: captain (1885), major (1888), colonel (1890) and general (1896). I n 1889, Crown Prince Rudolf, the son of Franz Josef, shot himself at his hunting lodge. The death of Prince Rudolf passed the crown to Franz Ferdinand's father, Carl Ludwig.When he died in 1896, Franz Ferdinand became the new heir to the throne. After the death of Franz, Austria/Hungary needed to enforce its authority in the face of such an insolent crime. Austria/Hungary immediately blamed Serbian government for the attack. After hearing that Serbia had asked Russia for help Austria/Hungary declared war on Serbia on July 28. However, with the threat of Russia and its army, and Austria having an army unprepared for a large-scale war, it required Germany's help to back up its words with force.Emperor Franz Josef wrote a personal letter to Kaiser Wilhelm asking for support and on July 6, Germany informed that they would give their full support to Austria. On August 1, after hearing news of Russia's general mobilization, Germany declared war on Russia. The German army then launched its attack on Russia's ally, France, through Belgium, violating Belgian neutrality and bringing Great Britain into the war as well. Over the next four years, the Great War/World War One grew to involve Italy, Japan, the Middle East and the United States, and many other countries.Around 20 million soldiers died and 21 million more were wounded and stuck with the damages for the rest of their lives. At last in 1919 peace was found but only stayed in peace for about two decades before giving way to another devastating world war. Who is to blame for the Great War? It comes down to who started it and who backed who which is firstly Austria/Hungary. After the assassination in Serbia they automatically blamed the city which caused a lot of tension and the declaring of war on one another. The fact that Austria/Hungary asked Germany for help encouraged Serbia to react with getting help with Russia and it went on and on.To summarise this blame answer its Germany and Austria/Hungary. Austria-Hung ary declared war on Serbia because a Serbian nationalist killed the heir to the throne. Germany's unconditional backing of Austria-Hungary encouraged them to be aggressive, which further lead to the Great War. To conclude this topic on what started and who was to blame for World War One I come to say that blame can cause a lot of damage and trouble eg. Austria blaming Serbia, and that the assassination of Franz grew way out of hand and could have been easily solved with no need of involvement with other contries. .